Thesis Defense: Dr. Robert Brown

Robert Brown successfully defended his thesis, “Methods and Models for the Analysis of Human Genetic Data,” on Wednesday, May 24, 2017 in Boelter 4760. His talk, which is posted on our YouTube channel ZarlabUCLA, discusses methods to better assess how human history affects genetics and how genetics affect human phenotypes such as height, eye color, and disease risk. Dr. Brown’s thesis presents five novel methods that build upon each other to analyze today’s large-scale human genetic data.

Dr. Robert Brown with his thesis committee. (L-R) Kirk Lohmueller, Janet Sinsheimer, Eleazar Eskin, Robert Brown, Bogdan Pasaniuc (committee chair), and Rita Cantor.

More details about Rob’s research are available in the following papers:

Robert Brown Gleb Kichaev, Nicholas Mancuso James Boocock ; Pasaniuc, Bogdan

Enhanced methods to detect haplotypic effects on gene expression Journal Article

In: Bioinformatics, pp. btx142, 2017.

Links | BibTeX

Robert Brown Hane Lee, Ascia Eskin Gleb Kichaev Kirk Lohmueller Bruno Reversade Stanley Nelson E F; Pasaniuc, Bogdan

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders Journal Article

In: European Journal of Human Genetics, 24 (1), pp. 113-119, 2016.

BibTeX

Brown, Robert; Lee, Hane; Eskin, Ascia; Kichaev, Gleb; Lohmueller, Kirk E; Reversade, Bruno; Nelson, Stanley F; Pasaniuc, Bogdan

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders. Journal Article

In: Eur J Hum Genet, 24 (1), pp. 113-9, 2015, ISSN: 1476-5438.

Abstract | Links | BibTeX

Brown, Robert; Pasaniuc, Bogdan

Enhanced methods for local ancestry assignment in sequenced admixed individuals Journal Article

In: PLoS Computational Biology, 10 (4), pp. e1003555, 2014.

BibTeX

YouTube: Robert Brown Thesis Defense

About Lana Martin

i write and teach.